Teogen Insight : Emerging Microbiology Innovations "From BCID2 Panels to Cytokine Signaling"
Improving the quality of life through microbiology
Leading Innovation in Microbiology, Diagnostics & Molecular Research
✔️ Molecular Biology Reagents
- PCR and qPCR kits for infectious diseases
- High-purity nucleic acid purification tools
- Beads and enzymes for NGS workflows
✔️ Specialized Research Molecules
- Bestatin 10 mg – Immunomodulatory peptide
- Sodium orthovanadate – Signal transduction inhibitor
- Cytokines, serotonin (5-HT), and microbiome regulators
✔️ Advanced Diagnostic Systems
- Rapid identification panels like the BCID2 panel
- Automated 5-part CBC machines for white blood cell analysis
- Biomarker-based kits for inflammation and infection detection (e.g., IL-18, IL-6)
🔍 What We Offer
🌡️ Microbiology at the Frontline of Discovery
🧫 BCID2 Panel: Transforming Bloodstream Infection Diagnosis
The BCID2 panel (BioFire®) is one of the most advanced molecular diagnostic tools available for rapid identification of bloodstream pathogens. Detecting over 43 targets—including bacteria, fungi, and antimicrobial resistance genes—the BCID2 panel provides results in under an hour.
It identifies critical resistance markers such as mecA, KPC, NDM, and vanA/B, making it essential in sepsis care and antimicrobial resistance monitoring.
🧪 AMPure XP Beads: DNA/RNA Purity You Can Trust
AMPure XP beads are magnetic bead-based reagents used to purify DNA or RNA during molecular workflows. In microbiology, they are crucial in:
- Shotgun metagenomics
- 16S rRNA sequencing
- Pathogen DNA clean-up from complex matrices
These beads ensure high-purity nucleic acids, free from PCR inhibitors, enabling accurate detection of microbial signatures in environmental, clinical, or gut microbiome samples.
🩸 5-Part CBC Machine: Where Hematology Meets Infection Science
Automated 5-part CBC machines provide differential white blood cell counts—crucial in determining infection patterns.
They distinguish:
- Neutrophilia → bacterial infections
- Lymphopenia → viral infections
- Eosinophilia → parasitic disease
When paired with molecular diagnostics or cytokine testing (e.g., IL-18), CBCs support accurate diagnosis and therapeutic monitoring.
💊 Bestatin 10 mg: Immune-Boosting Antibacterial Agent
Bestatin is a low-molecular-weight compound and potent aminopeptidase inhibitor that has immunostimulatory and antitumor effects.
In microbiology, Bestatin is gaining attention for:
- Enhancing antibiotic activity against MDR Gram-negative bacteria
- Modulating host immune response in infectious disease research
- Serving as a tool in immunotherapy and inflammation models
Sodium Orthovanadate: Unlocking Microbial Signal Transduction
Sodium orthovanadate is a well-known inhibitor of tyrosine phosphatases (PTPs), playing a critical role in host-pathogen signaling research.
Applications include:
- Studying bacterial kinase pathways
- Exploring immune evasion mechanisms
- Modulating phosphorylation events during infection
This reagent supports researchers exploring virulence factors, inflammation pathways, and the immune system’s molecular responses.
🧠 5-HT (Serotonin) and the Gut Microbiome
Did you know that over 90% of the body's serotonin (5-HT) is produced in the gut?
Emerging research links certain gut bacteria to 5-HT production, connecting the microbiome to the nervous system. Studies in neurogastroenterology now explore:
- Microbiome-mediated mood disorders
- Microbial impact on brain development and cognition
- Serotonin modulation as a therapeutic target
At Teogen, we support this frontier with reagents to study the microbiota-gut-brain axis.
🧬 IL-18: A Key Cytokine in Infection & Inflammation
Interleukin-18 (IL-18) is an innate immune cytokine elevated in bacterial, viral, and autoimmune conditions.
Its role in sepsis, tuberculosis, and COVID-19 has made IL-18 a critical biomarker for disease severity and progression.
- Researchers use IL-18 assays to:
- Predict clinical outcomes in infection
- Track cytokine storms
- Investigate macrophage activation pathways
IL-18 is a Teogen specialty reagent—validated for high-sensitivity immunoassays.
